General Cell Based Assays
Eurofins Discoverx PathHunter eXpress TIM3/TIM3 Dimerization Assay, 2-Plate Kit. (93-1082E3CP5M)
The PathHunter TIM3/TIM3 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand induced dimerization of TIM3/TIM3 receptors. This product uses EFC technology. The cell line included overexpresses TIM3 target protein fused to PK alongside TIM3 target protein fused to EA. Upon ligand-induced dimerization of TIM3/TIM3, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter CNR1 Bioassay Kit, 10-Plate. (93-0959Y2-00120)
The PathHunter CNR1 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. CP 55,940) based activation of CNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CNR1 and EA-tagged β-Arrestin-2. Activation of CNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Agilent Technologies SEAHORSE XF GLUCOSE/PYRUVATE O
Seahorse XF Glucose/Pyruvate Oxidation Stress Test Kit
Cayman Chemical AconItase FRrous AmonIM Su 1ea
An a1-adrenergic and 5-HT2A receptor antagonist (IC50s 2A- and a2B-adrenergic and 5-HT1A 5-HT1B 5-HT2B and 5-HT2C receptors (IC50s 18.1 4.89 4.68 41 11.5 and 26 nM respectively) among others decreases systolic and diastolic blood pressure and heart rate in spontaneously hypertensive rats and 2K-1C renal hypertensive dogs at 10 and 4 mg/kg respectively
Epigentek Inc Epigenase 5mC-Hydroxylase TET Activity/Inhibition Assay Kit (Fluorometric) (96 assays)
The Epigenase 5mC-Hydroxylase TET Activity/Inhibition Assay Kit (Fluorometric) is a complete set of optimized buffers and reagents for measuring activity/inhibition of total cytosine oxygenase TET enzymes in nuclear extracts or purified TET isoforms (TETs 1-3) from a broad range of species such as mammals, plants, fungi, and bacteria, and in a variety of forms including, but not limited to cultured cells and fresh and frozen tissues.
Abcam Aspartate Aminotransferase¿Activity Assay Kit
Aspartate Aminotransferase¿Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery U-PLEX Human TNF-B ASY
The Meso Scale Discovery U-PLEX Human TNF-beta Assay Kit is a multiplex immunoassay that measures TNF-beta levels in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay has high specificity and low cross-reactivity It includes a 96-well plate coated with capture antibodies detection antibodies labeled with electrochemiluminescent tags calibrators and buffer The kit allows simultaneous measurement of TNF-beta and other biomarkers It can be used for biomarker discovery lead optimization and diagnostics
Meso Scale Discovery U-PLEX Human TRAIL ASY
The U-PLEX Human TRAIL Assay K151XTK from Meso Scale Discovery is a multiplex immunoassay kit for the quantitative measurement of TRAIL in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and is provided in a 96-well plate format The kit includes a plate coated with capture antibodies detection antibodies calibrators and diluents The assay has a typical sensitivity of 0 3 pg/mL and an upper limit of quantification of 2500 pg/mL for TRAIL The total assay time is approximately 3 5 hours This product allows for the accurate quantitation of TRAIL across a wide dynamic range
Meso Scale Discovery U-PLEX Human G-CSF ASY 25 PL
The Meso Scale Discovery U-PLEX Human G-CSF Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of Granulocyte Colony Stimulating Factor (G-CSF) in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision with minimal matrix interference This assay requires 50 L or less sample volume and can be read on MSD instrument platforms It includes a plate coated with capture antibodies detection antibodies and calibrators and controls needed to generate a standard curve and measure G-CSF concentrations precisely
Meso Scale Discovery RPLEX HUM IGF2R/CIM6PR ASY
The Meso Scale Discovery IGF-2R (CI-MPR) Kit is an electrochemiluminescent immunoassay designed for the quantitative measurement of Insulin-like Growth Factor 2 Receptor (IGF-2R) in human serum plasma and cell culture supernatants This assay employs an MSD GOLD SULFO-TAG label and has a typical lower limit of detection of 0 03 ng/mL The kit includes a 96-well plate coated with an IGF-2R capture antibody a detection antibody conjugated to an MSD SULFO-TAG calibrators positive and negative controls 10X Read Buffer 10X Wash Buffer and Blocker A This assay can be run on the MESO QuickPlex SQ 120 MESO SECTOR S 600 or MESO SECTOR S 6000 instruments
Meso Scale Discovery R-PLEX Human ErbB3/HER3 ASY
The R-PLEX Human ERBB3 (HER3) Assay is a multiplex immunoassay kit by Meso Scale Diagnostics that enables the simultaneous quantitative measurement of ERBB3 and phospho-ERBB3 across multiple sites such as Y1289 Y1197 Y1262 Y1328 Y1199 Y1222 Y1276 and Y1298 It utilizes electrochemiluminescent detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample consumption This assay allows the study of ERBB3 signaling in human cell lines and tissues It requires an MSD instrument such as SECTOR Imager 2400 or 6000 for analysis
Cayman Chemical PhagocytosIs asy KItIgG-D 1ea
Cayman’s Phagocytosis Assay Kit (IgG-DyLight™ 405) employs latex beads coated with fluorescently-labeled rabbit IgG as a probe for the measurement of the phagocytic process in vitro. The engulfed fluorescent beads can be detected using a fluorescence microscope, allowing kinetic studies of phagocytosis at the single-cell level. In addition, the flow cytometric readout provides the advantage of visualizing perturbations in phagocytosis on the population level and, when combined with antibody staining, of specific cell types within complex populations. This kit provides enough Latex Beads-Rabbit IgG-DyLight™ 405 Complex for up to 500 samples.
Cayman Chemical GSH Co-Factr MIxture 1ea
A VOC and an isomer of pentanol a synthetic intermediate and an organic solvent that has been used in the synthesis of various compounds
Cayman Chemical cGAS InhIbItrCU-76 25uL
An internal standard for the quantification of bepotastine by GC- or LC-MS
Cayman Chemical CalcIum asy KIt 192Wel
Cayman's Calcium Assay provides a quick, reliable method for determining total calcium concentration in a variety of biological samples, as well as tissue homogenates and cell lysates. The assay utilizes an optimized variant of the well-established o-Cresolphthalein-calcium reaction in which a vivid purple complex that absorbs between 560 and 590 nm is formed in the presence of calcium.